Clinical trial publications

Sarris, J., Byrne, G. J., Bousman, C. A., Cribb, L., Savage, K. M., Holmes, O., . . . Stough, C. (2019). Kava for generalised anxiety disorder: A 16-week double-blind, randomised, placebo-controlled study. Australian and New Zealand Journal of Psychiatry. doi:10.1177/0004867419891246. https://pubmed.ncbi.nlm.nih.gov/31813230/

Arentz, S., Smith, C. A., Abbott, J., Fahey, P., Cheema, B. S., & Bensoussan, A. (2017). Combined Lifestyle and Herbal Medicine in Overweight Women with Polycystic Ovary Syndrome (PCOS): A Randomized Controlled Trial. Phytotherapy Research. doi:10.1002/ptr.5858. https://pubmed.ncbi.nlm.nih.gov/28685911/

Malhi, H. K., Tu, J., Riley, T. V., Kumarasinghe, S. P., & Hammer, K. A. (2016). Tea tree oil gel for mild to moderate acne; a 12 week uncontrolled, open-label phase II pilot study. The Australasian Journal Of Dermatology. doi:10.1111/ajd.12465. https://pubmed.ncbi.nlm.nih.gov/27000386/

Sarris, J., Stough, C., Bousman, C. A., Wahid, Z. T., Murray, G., Teschke, R., . . . Schweitzer, I. (2013). Kava in the treatment of generalized anxiety disorder: A double-blind, randomized, placebo-controlled study. Journal of Clinical Psychopharmacology, 33(5), 643-648. https://pubmed.ncbi.nlm.nih.gov/23635869/

Sarris, J., Scholey, A., Schweitzer, I., Bousman, C., LaPorte, E., Ng, C., . . . Stough, C. (2012). The acute effects of kava and oxazepam on anxiety, mood, neurocognition; and genetic correlates: A randomized, placebo-controlled, double-blind study. Human Psychopharmacology, 27(3), 262-269. https://pubmed.ncbi.nlm.nih.gov/22311378/

Tiralongo, E., Lea, R. A., Wee, S. S., Hanna, M. M., & Griffiths, L. R. (2012). Randomised, double blind, placebo-controlled trial of echinacea supplementation in air travellers. Evidence-Based Complementary and Alternative Medicine, 2012, 417267. doi:10.1155/2012/417267. https://pubmed.ncbi.nlm.nih.gov/22229040/

Abdul, M. I. M., Jiang, X., Williams, K. M., Day, R. O., Roufogalis, B. D., Liauw, W. S., . . . McLachlan, A. J. (2010). Pharmacokinetic and pharmacodynamic interactions of echinacea and policosanol with warfarin in healthy subjects. British Journal of Clinical Pharmacology, 69(5), 508-515. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2856051/pdf/bcp0069-0508.pdf

Barrett, B., Brown, R., Rakel, D., Mundt, M., Bone, K., Barlow, S., & Ewers, T. (2010). Echinacea for treating the common cold: a randomized trial. Annals of Internal Medicine, 153(12), 769-777. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3056276/pdf/nihms266207.pdf

Sarris, J., Kavanagh, D. J., Byrne, G., Bone, K. M., Adams, J., & Deed, G. (2009). The Kava Anxiety Depression Spectrum Study (KADSS): A randomized, placebo-controlled crossover trial using an aqueous extract of Piper methysticum. Psychopharmacology, 205(3), 399-407. https://pubmed.ncbi.nlm.nih.gov/19430766/

Sarris, J., Kavanagh, D. J., Deed, G., & Bone, K. M. (2009). St. John's wort and Kava in treating major depressive disorder with comorbid anxiety: A randomised double-blind placebo-controlled pilot trial. Human Psychopharmacology, 24(1), 41-48. https://pubmed.ncbi.nlm.nih.gov/19090505/

Van Die, M. D., Bone, K. M., Burger, H. G., Reece, J. E., & Teede, H. J. (2009). Effects of a combination of Hypericum perforatum and Vitex agnus-castus on PMS-like symptoms in late-perimenopausal women: Findings from a subpopulation analysis. Journal of Alternative and Complementary Medicine, 15(9), 1045-1048. https://pubmed.ncbi.nlm.nih.gov/19757982/

Van Die, M. D., Bone, K. M., Burger, H. G., & Teede, H. J. (2009). Are we drawing the right conclusions from randomised placebo-controlled trials? A post-hoc analysis of data from a randomised controlled trial. BMC Medical Research Methodology, 9(1). https://pubmed.ncbi.nlm.nih.gov/19549306/

Van Die, M. D., Burger, H. G., Bone, K. M., Cohen, M. M., & Teede, H. J. (2009). Hypericum perforatum with Vitex agnus-castus in menopausal symptoms: A randomized, controlled trial. Menopause, 16(1), 156-163. https://pubmed.ncbi.nlm.nih.gov/18791483/

Van Die, M. D., Teede, H. J., Bone, K. M., Reece, J. E., & Burger, H. G. (2009). Predictors of placebo response in a randomized, controlled trial of phytotherapy in menopause. Menopause, 16(4), 792-796. https://pubmed.ncbi.nlm.nih.gov/19587583/

Wheat, J., Currie, G., Kiat, H., & Bone, K. (2009). Improving lymphatic drainage with herbal preparations: A potentially novel approach to management of lymphedema. Australian Journal of Medical Herbalism, 21(3), 66-70. https://www.researchgate.net/publication/225090642_Improving_Lymphatic_Drainage_with_Herbal_Preparations_A_Potentially_Novel_Approach_to_Management_of_Lymphedema

Calabrese, C., Gregory, W. L., Leo, M., Kraemer, D., Bone, K., & Oken, B. (2008). Effects of a standardized Bacopa monnieri extract on cognitive performance, anxiety, and depression in the elderly: A randomized, double-blind, placebo-controlled trial. Journal of Alternative and Complementary Medicine, 14(6), 707-713. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153866/pdf/acm.2008.0018.pdf

Matthias, A., Addison, R. S., Agnew, L. L., Bone, K. M., Watson, K., & Lehmann, R. P. (2007). Comparison of Echinacea alkylamide pharmacokinetics between liquid and tablet preparations. Phytomedicine, 14(9), 587-590. https://pubmed.ncbi.nlm.nih.gov/17289362/

Gordon, A., Hobbs, D. A., Bowden, D. S., Bailey, M. J., Mitchell, J., Francis, A. J., & Roberts, S. K. (2006). Effects of Silybum marianum on serum hepatitis C virus RNA, alanine aminotransferase levels and well-being in patients with chronic hepatitis C. Journal of Gastroenterology and Hepatology (Australia), 21, 275-280. https://pubmed.ncbi.nlm.nih.gov/16460486/

Leach, M. J., Pincombe, J., & Foster, G. (2006). Clinical efficacy of horsechestnut seed extract in the treatment of venous ulceration. Journal of Wound Care, 15(4), 159-167. doi:10.12968/jowc.2006.15.4.26898 https://pubmed.ncbi.nlm.nih.gov/16620045/

Agnew, L. L., Guffogg, S. P., Matthias, A., Lehmann, R. P., Bone, K. M., & Watson, K. (2005). Echinacea intake induces an immune response through altered expression of leucocyte hsp70, increased white cell counts and improved erythrocyte antioxidant defences. Journal of Clinical Pharmacy and Therapeutics, 30(4), 363-369. https://pubmed.ncbi.nlm.nih.gov/15985050/

Lauten, J. D., Boyd, L., Hanson, M. B., Lillie, D., Gullion, C., & Madden, T. E. (2005). A clinical study: Melaleuca, Manuka, Calendula and green tea mouth rinse. Phytotherapy Research, 19(11), 951-957. https://pubmed.ncbi.nlm.nih.gov/16317652/

Matthias, A., Addison, R. S., Penman, K. G., Dickinson, R. G., Bone, K. M., & Lehmann, R. P. (2005). Echinacea alkamide disposition and pharmacokinetics in humans after tablet ingestion. Life Sciences, 77(16), 2018-2029. https://pubmed.ncbi.nlm.nih.gov/15919096/

Coxeter, P. D., Schluter, P. J., Eastwood, H. L., Nikles, C. J., & Glasziou, P. P. (2003). Valerian does not appear to reduce symptoms for patients with chronic insomia in general practice using a series of randomised n-of-1 trials. Complementary Therapies in Medicine, 11(4), 215-222. https://pubmed.ncbi.nlm.nih.gov/15022653/

Francis, A. J. P., & Dempster, R. J. W. (2002). Effect of valerian, Valeriana edulis, on sleep difficulties in children with intellectual deficits: Randomised trial. Phytomedicine, 9(4), 273-279. https://pubmed.ncbi.nlm.nih.gov/12120807/

Gaffney, B. T., Hügel, H. M., & Rich, P. A. (2001). The effects of Eleutherococcus senticosus and Panax ginseng on steroidal hormone indices of stress and lymphocyte subset numbers in endurance athletes. Life Sciences, 70(4), 431-442. https://pubmed.ncbi.nlm.nih.gov/11798012/